Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Eomes  eomesodermin   (Synonyms: Tbr2)
Results	Reference
1	J:277749 Barber M, Andrews WD, Memi F, Gardener P, Ciantar D, Tata M, Ruhrberg C, Parnavelas JG, Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain. Cereb Cortex. 2018 Jul 1;28(7):2577-2593
1	J:242500 Barford K, Yap CC, Dwyer ND, Winckler B, The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. J Comp Neurol. 2017 Jun 01;525(8):1861-1878
1	J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163
1	J:269810 Bian S, Hong J, Li Q, Schebelle L, Pollock A, Knauss JL, Garg V, Sun T, MicroRNA cluster miR-17-92 regulates neural stem cell expansion and transition to intermediate progenitors in the developing mouse neocortex. Cell Rep. 2013 May 30;3(5):1398-1406
1	J:159309 Buttner N, Johnsen SA, Kugler S, Vogel T, Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7042-7
1	J:224504 Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L, Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014;5:3885
1	J:235316 Chen Q, Arai D, Kawakami K, Sawada T, Jing X, Miyajima M, Hirai S, Sakaguchi K, Furushima K, EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling. PLoS One. 2015;10(5):e0126942
1	J:163236 Cheng A, Scott AL, Ladenheim B, Chen K, Ouyang X, Lathia JD, Mughal M, Cadet JL, Mattson MP, Shih JC, Monoamine oxidases regulate telencephalic neural progenitors in late embryonic and early postnatal development. J Neurosci. 2010 Aug 11;30(32):10752-62
1	J:262044 Chodelkova O, Masek J, Korinek V, Kozmik Z, Machon O, Tcf7L2 is essential for neurogenesis in the developing mouse neocortex. Neural Dev. 2018 May 11;13(1):8
1*	J:308933 Chowdhury R, Wang Y, Campbell M, Goderie SK, Doyle F, Tenenbaum SA, Kusek G, Kiehl TR, Ansari SA, Boles NC, Temple S, STAU2 binds a complex RNA cargo that changes temporally with production of diverse intermediate progenitor cells during mouse corticogenesis. Development. 2021 Aug 1;148(15):dev199376
1	J:197151 Cloetta D, Thomanetz V, Baranek C, Lustenberger RM, Lin S, Oliveri F, Atanasoski S, Ruegg MA, Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis. J Neurosci. 2013 May 1;33(18):7799-810
1	J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93
1	J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35
1	J:244825 Dennis DJ, Wilkinson G, Li S, Dixit R, Adnani L, Balakrishnan A, Han S, Kovach C, Gruenig N, Kurrasch DM, Dyck RH, Schuurmans C, Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4934-E4943
1	J:285490 Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC, FMRP Modulates Neural Differentiation through m(6)A-Dependent mRNA Nuclear Export. Cell Rep. 2019 Jul 23;28(4):845-854.e5
1	J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95
1	J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11
1	J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420
1*	J:266159 Hara T, Maejima I, Akuzawa T, Hirai R, Kobayashi H, Tsukamoto S, Tsunoda M, Ono A, Yamakoshi S, Oikawa S, Sato K, Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development. PLoS Genet. 2018 Sep;14(9):e1007647
1	J:179804 Harrison SJ, Nishinakamura R, Jones KR, Monaghan AP, Sall1 regulates cortical neurogenesis and laminar fate specification in mice: implications for neural abnormalities in Townes-Brocks syndrome. Dis Model Mech. 2012 May;5(3):351-65
1	J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631
1	J:238096 Houlihan SL, Lanctot AA, Guo Y, Feng Y, Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife. 2016 Sep 24;5:e17823
1	J:294837 Huang C, Liu T, Wang Q, Hou W, Zhou C, Song Z, Shi YS, Gao X, Chen G, Yin Z, Hu Y, Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development. Cereb Cortex. 2020 Jun 1;30(7):4183-4196
1	J:171878 Imamura O, Pages G, Pouyssegur J, Endo S, Takishima K, ERK1 and ERK2 are required for radial glial maintenance and cortical lamination. Genes Cells. 2010 Oct;15(10):1072-88
1	J:173598 Jacquet BV, Muthusamy N, Sommerville LJ, Xiao G, Liang H, Zhang Y, Holtzman MJ, Ghashghaei HT, Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb. J Neurosci. 2011 Jun 22;31(25):9368-82
1	J:241995 Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V, Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell. 2017 Jun 05;41(5):481-495.e5
1	J:252977 Jourdon A, Gresset A, Spassky N, Charnay P, Topilko P, Santos R, Prss56, a novel marker of adult neurogenesis in the mouse brain. Brain Struct Funct. 2016 Dec;221(9):4411-4427
1	J:196454 Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS, Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 2013 Apr 4;12(4):440-52
1	J:158531 Kawase-Koga Y, Low R, Otaegi G, Pollock A, Deng H, Eisenhaber F, Maurer-Stroh S, Sun T, RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells. J Cell Sci. 2010 Feb 15;123(Pt 4):586-94
1	J:228845 Kim E, Wang Y, Kim SJ, Bornhorst M, Jecrois ES, Anthony TE, Wang C, Li YE, Guan JL, Murphy GG, Zhu Y, Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. Elife. 2014;3
1	J:219376 La Fata G, Gartner A, Dominguez-Iturza N, Dresselaers T, Dawitz J, Poorthuis RB, Averna M, Himmelreich U, Meredith RM, Achsel T, Dotti CG, Bagni C, FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry. Nat Neurosci. 2014 Dec;17(12):1693-700
1	J:178681 Lakoma J, Garcia-Alonso L, Luque JM, Reelin sets the pace of neocortical neurogenesis. Development. 2011 Dec;138(23):5223-34
1	J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49
1	J:312817 Lei X, Jiao J, UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. Stem Cell Reports. 2018 Apr 10;10(4):1193-1207
1	J:261049 Leone DP, Srinivasan K, Brakebusch C, McConnell SK, The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol. 2010 Aug;70(9):659-78
1	J:143512 Li G, Kataoka H, Coughlin SR, Pleasure SJ, Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development. 2009 Jan;136(2):327-35
1	J:337597 Li J, Jiang H, Mu Y, Wei Z, Ma A, Sun M, Zhao J, Zhu C, Chen X, SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex. iScience. 2023 Jul 21;26(7):107042
1	J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780
1	J:307535 Liu X, Schneble-Lohnert N, Kristofova M, Qing X, Labisch J, Hofmann S, Ehrenberg S, Sannai M, Jorss T, Ori A, Godmann M, Wang ZQ, The N-terminal BRCT domain determines MCPH1 function in brain development and fertility. Cell Death Dis. 2021 Feb 1;12(2):143
1	J:343071 Lopez-Tobon A, Shyti R, Villa CE, Cheroni C, Fuentes-Bravo P, Trattaro S, Caporale N, Troglio F, Tenderini E, Mihailovich M, Skaros A, Gibson WT, Cuomo A, Bonaldi T, Mercurio C, Varasi M, Osborne L, Testa G, GTF2I dosage regulates neuronal differentiation and social behavior in 7q11.23 neurodevelopmental disorders. Sci Adv. 2023 Dec;9(48):eadh2726
1	J:291493 Najas S, Pijuan I, Esteve-Codina A, Usieto S, Martinez JD, Zwijsen A, Arbones ML, Marti E, Le Dreau G, A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex. Development. 2020 Jul 13;147(13):dev187005
1	J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51
1	J:180141 Qin S, Liu M, Niu W, Zhang CL, Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21117-21
1	J:266669 Rash BG, Micali N, Huttner AJ, Morozov YM, Horvath TL, Rakic P, Metabolic regulation and glucose sensitivity of cortical radial glial cells. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10142-10147
1	J:154951 Sahara S, O'Leary DD, Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Neuron. 2009 Jul 16;63(1):48-62
1	J:241756 Sanchez-Camacho C, Ortega JA, Ocana I, Alcantara S, Bovolenta P, Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Dev Neurobiol. 2011 May;71(5):337-50
1	J:216471 Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X, Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4086-95
1	J:285212 Shohayeb B, Ho U, Yeap YY, Parton RG, Millard SS, Xu Z, Piper M, Ng DCH, The association of microcephaly protein WDR62 with CPAP/IFT88 is required for cilia formation and neocortical development. Hum Mol Genet. 2020 Jan 15;29(2):248-263
1	J:308820 Shohayeb B, Ho UY, Hassan H, Piper M, Ng DCH, The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus. Front Cell Dev Biol. 2020;8:549353
1	J:138025 Siegenthaler JA, Tremper-Wells BA, Miller MW, Foxg1 haploinsufficiency reduces the population of cortical intermediate progenitor cells: effect of increased p21 expression. Cereb Cortex. 2008 Aug;18(8):1865-75
1	J:137035 Solberg N, Machon O, Krauss S, Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. Dev Dyn. 2008 Jul;237(7):1799-811
1	J:268892 Tsiarli MA, Paula Monaghan A, Defranco DB, Differential subcellular localization of the glucocorticoid receptor in distinct neural stem and progenitor populations of the mouse telencephalon in vivo. Brain Res. 2013 Jul 26;1523:10-27
1	J:197141 Tuoc TC, Boretius S, Sansom SN, Pitulescu ME, Frahm J, Livesey FJ, Stoykova A, Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell. 2013 May 13;25(3):256-69
1	J:293532 Vaid S, Camp JG, Hersemann L, Eugster Oegema C, Heninger AK, Winkler S, Brandl H, Sarov M, Treutlein B, Huttner WB, Namba T, A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex. Development. 2018 Oct 18;145(20):dev169276
1	J:298832 Wang H, Xiao Z, Zheng J, Wu J, Hu XL, Yang X, Shen Q, ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development. Cell Rep. 2019 May 21;27(8):2335-2353.e6
1*	J:258043 Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler-Reya RJ, Zhang Z, Ogawa Y, Kellis M, Duester G, Zhao JC, N(6)-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications. Nat Neurosci. 2018 Feb;21(2):195-206
1	J:292913 Will L, Portegies S, van Schelt J, van Luyk M, Jaarsma D, Hoogenraad CC, Dynein activating adaptor BICD2 controls radial migration of upper-layer cortical neurons in vivo. Acta Neuropathol Commun. 2019 Oct 26;7(1):162
1	J:293436 Wilson SL, Kalinovsky A, Orvis GD, Joyner AL, Spatially restricted and developmentally dynamic expression of engrailed genes in multiple cerebellar cell types. Cerebellum. 2011 Sep;10(3):356-72
1	J:171660 Winpenny E, Lebel-Potter M, Fernandez ME, Brill MS, Gotz M, Guillemot F, Raineteau O, Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Dev. 2011;6:12
1*	J:124867 Wrobel CN, Mutch CA, Swaminathan S, Taketo MM, Chenn A, Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors. Dev Biol. 2007 Sep 15;309(2):285-97
1	J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272
1	J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27
1	J:247703 Yoon KJ, Ringeling FR, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Dore LC, Jin P, Regot S, Zhuang X, Canzar S, He C, Ming GL, Song H, Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation. Cell. 2017 Nov 02;171(4):877-889.e17